Dr. Inessa KhaykisM.D., practices at Vanguard Gastroenterology located in New York City, NY.

Dr. Inessa Khaykis combines extensive experience in digestive health with a thoughtful, personal approach to care. She listens carefully, explains findings clearly, and works with each patient to develop a treatment plan that reflects their medical needs, daily life, and priorities.

Her practice encompasses common digestive concerns and complex gastrointestinal conditions. Patients see her for acid reflux, abdominal pain, bloating, swallowing difficulties, irritable bowel syndrome, constipation, diarrhea, inflammatory bowel disease, and liver disorders. She understands how disruptive persistent symptoms can be and helps patients work toward answers and meaningful relief. Colon cancer screening and prevention are central to her practice.

Dr. Khaykis also has specialized expertise in endoscopic ultrasound and capsule endoscopy, which allow detailed evaluation of pancreatic cysts, pancreatic and bile duct disorders, abnormalities within or near the digestive tract, and small bowel conditions.

She completed her internal medicine residency, chief residency, and gastroenterology fellowship at NYU School of Medicine, followed by advanced training in endoscopic ultrasound at Columbia University Medical Center. She serves as Director of Endoscopy at Northwell Greenwich Village Hospital and Practice Director of Vanguard Gastroenterology and Primary Care.

An educator and contributor to clinical research, Dr. Khaykis has trained gastroenterologists and held national leadership roles within the American Society for Gastrointestinal Endoscopy. She serves on the editorial board of Gastrointestinal Endoscopy and contributes to national initiatives to improve colorectal cancer screening.

Dr. Khaykis has been repeatedly recognized as a Castle Connolly Top Doctor and among New York Magazine’s Top Doctors, and has received Castle Connolly’s Exceptional Women in Medicine distinction from 2019 through 2026.

Whether patients come for preventive screening or a complicated digestive problem, her goal is to help them feel heard, understand their health, and feel confident in their care.